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L-Asparagine is a non-essential(1) amino acid because it can be synthesized in the body from Aspartic acid. Its chemical structure is identical to that of Aspartic acid, except one side chain is linked to ammonia, making it an Amide.

It serves as an amino donor in a certain type of transamination(2) in the liver. Asparagine participates in the metabolic control of the functions of brain cells and nervous system.


  • Asparagine is a nontoxic carrier of residual ammonia to be eliminated from the body
  • Asparagine is used in the treatment of the brain and nervous system
  • Asparagine plays a key role in the biosynthesis of glycoproteins
  • The human nervous system needs Asparagine to be able to maintain an equilibrium
  • Asparagine increases resistance to fatigue
  • Asparagine helps amino acids convert to what they are supposed to in the liver
  • The benefits of Asparagine work to protect nerve and liver health

Deficiency Symptoms

  • Gall bladder dysfunction
  • Liver trouble

Addictive Substances Used

  • Research is lacking with no identifiable evidence of the use of addictive substances when the human body lacks Asparagine

Body Systems, Glands & Organs Affected

  • Liver
  • Thymus
  • Lymph System
  • Nervous System

Complimentary Vitamins

  • Vitamin A
  • Niacin
  • Choline
  • Inositol

Complimentary Minerals

  • Chromium
  • Zinc

Food Sources

  • Asparagus
  • Poultry
  • Seafood
  • Most abundant in asparagus juice
  • Beef
  • Eggs

Potential Precautions


(1) Non-essential means the human body can produce the nutrient on its own with proper nutrition.

(2) Transamination: a chemical reaction that transfers an amino group to a keto acid to form new amino acids. This pathway is responsible for the deamination of most amino acids.

(3) According to a 2018 article in The Guardian, a study found that decreasing levels of asparagine “dramatically” reduced the spread of breast cancer in laboratory mice. The article noted that similar studies had not been conducted in humans.

(4) The mice were in-bred to lack immunity  and then injected with cancer cells and were not fed asparagus.

Supporting Research

National Center for Biotechnology Information (2021). PubChem Compound Summary for CID 6267, Asparagine. Retrieved February 3, 2021 from https://pubchem.ncbi.nlm.nih.gov/compound/Asparagine.

Lepore, D., ND. (1985). The Ultimate Healing System: The Illustrated Guide to Muscle Testing & Nutrition. Woodland Pub.

Asparagine. (2018, June 12). Retrieved February 03, 2021, from https://aminoacidsguide.com/Asn.html

Sample I (2018-02-07). “Spread of breast cancer linked to compound in asparagus and other foods”The Guardian. Retrieved 2021-02-04

Knott SR, Wagenblast E, Khan S, Kim SY, Soto M, Wagner M, et al. (February 2018). “Asparagine bioavailability governs metastasis in a model of breast cancer”Nature554 (7692): 378–381. Bibcode:2018Natur.554..378Kdoi:10.1038/nature25465PMC 5898613PMID 29414946.